Figure 6
Knockdown of PDGFBB restrained the growth of xenografts in vivo. (A) The obtained xenografts after HSV administration for 6 weeks (n = 8–9). (B) The PDGFB and PDGFA expression in xenografts after HSV administration for 6 weeks (n = 6). (C) The tumor volume from 0 to 6 weeks of HSV administration (n = 8–9). (D) The body weight of nude mice from 0 to 6 weeks of HSV administration (n = 8–9). (E) PETCT images showed the cross sections of xenograft, lung, encephalocoele and liver in nude mice (n = 3). (F) The SUXmax in the xenograft, lung, encephalocoele and liver after HSV administration for 6 weeks (n = 3). *HSV-PDGFi-shRNA group vs vector group, *P < 0.05, **P < 0.01 by student t-test (B, F) or/and two-way ANOVA (C, D).
