Figure 8 | Scientific Reports

Figure 8

From: PDGFBB facilitates tumorigenesis and malignancy of lung adenocarcinoma associated with PI3K-AKT/MAPK signaling

Figure 8

PDGFBB induced the activation of PI3K/AKT and MAPK signaling. The protein expression of ERK1/2, p-ERK1/2, AKT and p-AKT in A549 (A–C) and SPCA1 (D–F) cells after administrated with exogenous PDGFBB (20 ng/ml) or transfected with HSV-PDGFi shRNA for 48 h. shRNA: HSV-PDGFi shRNA. *P < 0.05, **P < 0.01, ***P < 0.001 by one-way ANOVA (B, C, E, F).

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