Table 4 Patient VTE risk and compliance with AOA VTE Prevention Guidelines (2018) (N = 1838).

From: Compliance with Australian Orthopaedic Association guidelines does not reduce the risk of venous thromboembolism after total hip and knee arthroplasty

Patient-level risk

N (%)

Criteria for high PE risk

Major criteria (one or more):

174 (9.5%)

Minor criteria (three or more)††

96 (5.2%)

High VTE risk (≥ 1 major criteria or  ≥ 3minor criteria)

230 (12.5%)

Routine VTE risk (did not meet high VTE risk criteria)

1554 (82.9%)

High risk of bleeding*** (known bleeding disorder)

53 (2.9%)

Prophylaxis received^

 (i) Sequential compression device

1683 (91.6)

 (ii) Aspirin- 100–300 mg per day

836 (44.6%)

 (iii) Potent anticoagulation (LMWH, Warfarin, DOAC)

1484 (79.1%)

Proportion of cohort who received prophylaxis compliant with routine and high VTE risk and high bleeding risk recommendations^

 (1) Compliant with routine recommended care (i. & ii &/or iii.)

1675 (91.2%)

 (2) Compliant with high VTE risk recommendations (i and iii only, did not receive aspirin unless taking preoperatively)

1142 (62.2%)

 (3) High bleeding risk VTE prophylaxis recommendations (i. only)

7 (0.4%)

Patients received recommended prophylaxis for the assessed risk level (Patient risk-stratified compliant prophylaxis)

 (1) People at routine VTE risk (N = 1554) who received routine VTE risk compliant prophylaxis

1411 (76.8%)

 (2) High VTE risk (N = 230) who received high VTE risk compliant VTE prophylaxis

168 (9.1%)

 (3) High bleeding risk (N = 54) who received high bleeding risk compliant VTE prophylaxis

0 (0%)

Elements of compliance

A. Received risk-stratified recommended prophylaxis (1 + 2 + 3)

1579 (85.9%)

Recommended duration

Three to six weeks (recommended)

1035 (56.3%)

 (i) At least 21 days (considered compliant)

1137 (61.9%)

 (ii) Ceased prophylaxis to start VTE treatment (compliant)

42 (2.3%)

B. Compliant with recommended duration (i. or ii)¥

1169 (63.6%)

Other general recommendations

 (i) Received neuraxial anaesthesia (N = 1837) (1179 compliant)

1151 (62.7%)

 (ii) Neuraxial anaesthesia contraindicated (on warfarin)

68 (3.6%)

 (iii) Bleeding mitigation (received tranexamic acid)

1115 (59.5%)

 (iv) Ceased preoperative warfarin within 5 days of surgery

37 (2.0%)

 (v) Ceased preoperative clopidogrel within 5 days of surgery

45 (2.5%)

 (vi) Early mobilisation (walked day 0 or day 1)

1376 (75.0%)

C. Compliant with all relevant general recommendations (i. to vi.)

592 (32.2%)

Overall AOA compliance (compliant with A and B and C)

258 (14.0%)

  1. ***30 people at high bleeding risk also met criteria for high VTE risk and were considered at high bleeding risk.
  2. ††12 people met criteria for both minor and major high-risk factors for PE.
  3. ^Regardless of patient level risk, categories not exclusive.
  4. ¥10 people had at least 21 days prophylaxis duration and eased VTE prophylaxis to commence treatment.
  5. Only considered if taking preoperative warfarin or clopidogrel.