Table 1 Baseline characteristics in 306 patients who underwent laparoscopic colorectal resection: comparison between high-TMI and low-TMI groups.
Variables | Total | High-TMI | Low-TMI | p-value |
|---|---|---|---|---|
n (%) or median (range) | ||||
Patients | 306 | 122 (39.8%) | 184 (60.2%) | |
Age (years) | 71.5 ± 11.0 | 72.1 ± 10.9 | 71.1 ± 11.1 | 0.41 |
Sex | ||||
Male | 192 (63%) | 79 (64.7%) | 113 (61.4%) | 0.55 |
Female | 114 (37%) | 43 (35%) | 71 (38.5%) | |
Body mass index (kg/m2) | 22.6 ± 4.12 | 21.8 ± 4.05 | 23.1 ± 4.09 | 0.003 |
Tumor location | 0.06 | |||
Right-sided cancer | 89 (29%) | 28 (22.3%) | 61 (33.1%) | |
Left-sided cancer | 217 (71%) | 94 (77.0%) | 123 (66.8%) | |
Obstructive cancer | 22 (7.2%) | 13 (10.6%) | 9 (4.9%) | 0.06 |
CEA (ng/mL) | 9.8 ± 24.8 | 19.8 ± 37.1 | 3.26 ± 3.43 | < 0.001 |
CA19-9 (U/mL) | 21.1 ± 43.9 | 42.6 ± 63.6 | 6.73 ± 5.22 | < 0.001 |
Histopathology | 0.20 | |||
tub1 | 147 (48%) | 53 (43.4%) | 94 (51.0%) | |
tub2 | 147 (48%) | 62 (50.8%) | 85 (46.2%) | |
por | 4 (1.3%) | 1 (0.8%) | 3 (1.6%) | |
Others | 8 (2.7%) | 6 (4.9%) | 2 (1.1%) | |
T factor | < 0.001 | |||
T1 | 63 (21%) | 12 (9.8%) | 51 (27.7%) | |
T2 | 48 (16%) | 16 (13.1%) | 32 (17.3%) | |
T3 | 173 (57%) | 82 (67.2%) | 91 (49.4%) | |
T4 | 22 (7.2%) | 12 (9.8%) | 10 (5.4%) | |
N factor | < 0.001 | |||
N0 | 189 (62%) | 60 (49.2%) | 129 (70.1%) | |
N1 | 76 (25%) | 34 (27.8%) | 42 (22.8%) | |
N2 | 36 (12%) | 25 (20.4%) | 11 (5.9%) | |
N3 | 5 (1.6%) | 3 (2.5%) | 2 (1.1%) | |
Pathological stage | < 0.001 | |||
I | 92 (30.1%) | 21 (17.2%) | 71 (38.6%) | |
II | 97 (32%) | 39 (31.9%) | 58 (31.5%) | |
III | 117 (38%) | 62 (50.8%) | 55 (29.8%) | |
Operative procedure | 0.28 | |||
Ileocecal resection | 40 (13%) | 11 (9.0%) | 29 (15.7%) | |
Right hemicolectomy | 45 (15%) | 17 (13.9%) | 28 (15.2%) | |
Transverse colectomy | 3 (1.0%) | 0 (0%) | 3 (1.9%) | |
Left hemicolectomy | 17 (5.6%) | 6 (4.9%) | 11 (5.9%) | |
Sigmoid colectomy | 99 (32%) | 39 (31.9%) | 60 (32.6%) | |
Low anterior resection | 67 (22%) | 32 (26.2%) | 35 (19.0%) | |
Abdominoperineal resection | 35 (11%) | 17 (13.9%) | 18 (9.8%) | |
Lymph node dissection | 0.37 | |||
D1 | 14 (4.6%) | 6 (4.9%) | 8 (4.4%) | |
D2 | 117 (38%) | 53 (43.4%) | 64 (34.7%) | |
D3 | 175 (57%) | 63 (51.6%) | 112 (60.8%) | |
Operative time (min) | 272.7 ± 78.4 | 289.2 ± 84.1 | 261.8 ± 72.5 | 0.005 |
Intraoperative blood loss (mL) | 69.6 ± 150.8 | 83.3 ± 197.0 | 60.5 ± 109.8 | 0.70 |
Postoperative complication | ||||
Anastomotic leakage | 13 (4.3%) | 9 (7.4%) | 4 (2.1%) | 0.03 |
Surgical site infection | 47 (15%) | 21 (17.2%) | 26 (14.2%) | 0.47 |
Ileus | 37 (12%) | 24 (19.6%) | 13 (7.0%) | 0.001 |
Intraperitoneal abscess | 13 (4.3%) | 8 (6.5%) | 5 (2.7%) | 0.10 |
Adjuvant chemotherapy | 126 (41%) | 64 (52.4%) | 62 (33.7%) | 0.001 |
High-NLR | 46 (15%) | 24 (19.6%) | 22 (11.9%) | 0.06 |
High-PLR | 152 (49.6%) | 60 (49.1%) | 92 (50.0%) | 0.88 |
GPS, 1 or 2 | 67 (21.9%) | 33 (27.0%) | 34 (18.5%) | 0.08 |
Smoking history | 109 (35.6%) | 45 (36.8%) | 64 (34.8%) | 0.70 |
Liver cirrhosis | 9 (2.9%) | 3 (2.4%) | 6 (3.3%) | 0.68 |
Diabetes mellitus | 59 (19.2%) | 25 (20.5%) | 34 (18.5%) | 0.66 |
