Table 2 Univariate and multivariate analyses of relapse-free survival in patients with colorectal cancer after surgery.
Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
HR (95% CI) | p-value | HR (95% CI) | p-value | |
Age, ≥ 65 years | 1.78 (0.87–3.61) | 0.11 | ||
Sex, male | 1.40 (0.80–2.45) | 0.23 | ||
Right-sided cancer | 0.92 (0.52–1.63) | 0.77 | ||
Obstructive colorectal cancer | 2.70 (1.32–5.51) | < 0.01 | 1.38 (0.67–2.86) | 0.37 |
CEA, ≥ 5.0 ng/mL | 3.15 (1.87–5.30) | < 0.01 | ||
CA19-9, ≥ 37.0 U/mL | 3.15 (1.73–5.76) | < 0.01 | ||
T factor, T3 or higher | 5.75 (2.46–13.4) | < 0.01 | 2.69 (1.12–6.45) | 0.026 |
Stage III | 6.06 (3.32–11.1) | < 0.01 | 3.30 (1.74–6.28) | < 0.001 |
Lymphovascular invasion, positive | 7.19 (2.25–23.0) | < 0.01 | 2.57 (0.75–8.73) | 0.13 |
Complications, including leakage or ileus | 1.50 (0.65–3.50) | 0.34 | ||
GPS, 1 or 2 | 1.29 (0.71–2.36) | 0.40 | ||
High-NLR | 1.56 (0.81–3.02) | 0.18 | ||
High-PLR | 1.16 (0.69–1.94) | 0.57 | ||
High-TMI | 3.70 (2.13–6.41) | < 0.01 | 2.51 (1.43–4.38) | 0.001 |
