Table 1 Baseline characteristics.

From: Development of a deep learning model to distinguish the cause of optic disc atrophy using retinal fundus photography

 

Leber’s hereditary optic neuropathy

Optic neuritis

P-valuea

No. of patients (eyes)

15 (30)

26 (30)

–

Sex (male/female)

10/5

12/14

–

Diagnosis age

28.3 ± 18.51

47.1 ± 19.7

–

Laterality (Right/Left)

15/15

10/20

–

Visual field 30–2 mean deviation (dB)

− 9.38 ± 9.24

− 7.02 ± 10.79

0.536

Retinal nerve fiber layer thickness (μm)b

76.87 ± 13.01

80.91 ± 18.69

0.725

Ganglion cell Layer thickness (μm)c

69.56 ± 14.36

75.95 ± 15.98

0.675

  1. aMann–Whitney U test.
  2. bA macular scan of each participant’s eye was obtained using the macular cube 200 × 200 scan protocols. Ganglion cell-inner plexiform layer thickness (GCIPL) values were obtained using the ganglion cell analysis algorithm from an elliptical annulus localized on the fovea center; the average GCIPL thickness were measured.
  3. CThe average retinal nerve fiber layer thickness measurements were also assessed with the 6 mm × 6 mm data cube captured by the Optic Disc Cube 200 × 200 scan (Cirrus™; Carl Zeiss Meditec, Inc., Dublin, CA, USA).