Table 1 The summary table of average LINE-1 region methylation level in study cohort.

From: Prolonged culturing of colonic epithelial organoids derived from healthy individuals and ulcerative colitis patients results in the decrease of LINE-1 methylation level

 

CON

Active UC

Quiescent UC

Biopsy, %

 Mean ± SD

68.7 ± 4.3

66.7 ± 4.4

69.4 ± 2.9

Crypts, %

 Mean ± SD

68.6 ± 4.9

66.3 ± 4.6

67.9 ± 3.7

Organoids_P0

 Mean ± SD

66.9 ± 4.1

65.6 ± 4.2

66.0 ± 3.9

Organoids_P1

 Mean ± SD

66.5 ± 5.4

61.8 ± 3.8

65.5 ± 3.7

Organoids_P5

 Mean ± SD

60.6 ± 2.3

62.6 ± 4.8

64.4 ± 3.9

  1. SD—standard deviation, CON—control, UC—ulcerative colitis.
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