Table 2 Demographic and clinical characteristics of the subjects.

From: Prolonged culturing of colonic epithelial organoids derived from healthy individuals and ulcerative colitis patients results in the decrease of LINE-1 methylation level

 

CON, n = 6

Active UC, n = 6

Quiescent UC, n = 7

Age

 Mean ± SD

53.2 ± 8.5

43.7 ± 19.3

40.4 ± 12.7

Sex, n (%)

 Female

3 (50.0)

3 (50.0)

3 (43.0)

Full Mayo score

 Min–max

-

4–8

0–2

Biopsy site, n (%)

 Sigmoid colon

3 (50.0)

2 (33.0)

5 (71.00)

 Rectum

2 (33.0)

2 (33.0)

1 (14.0)

 Descending colon

1 (17.0)

2 (33.0)

1 (14.0)

Extent of UC, n (%)

 Proctitis (E1)

-

0 (0.0)

1 (14.0)

 Left-sided colitis (E2)

-

1 (17.0)

2 (28.0)

 Extensive colitis (E3)

-

5 (83.0)

4 (57.0)

Previous treatment (Yes/No)

 Immunosuppressants

-

No

Yes

 Anti-inflammatory agents

-

Yes

Yes

  1. SD—standard deviation, CON—control, UC—ulcerative colitis.
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