Table 10 The optimization sets used to select the best models for high-grade intraprostatic intraepithelial neoplasia, vessel, nerve, and inflammatory cell infiltration.
Finding | Regions, n (case, n) | Magnification level | Positive, n (%) | Negative, n (regions, n; cases, n) | List of negative findings (%) |
|---|---|---|---|---|---|
Cribriform pattern | 87 (12) | 10× | 197 (32.9) | 402 (67.1) (197, 25) | Gleason pattern 3 (41.0) Gleason pattern 4 without cribriform pattern (9.4) Nerve (36.7) Normal glandular tissues (12.9) |
Ductal morphology | 36 (1) | 10× | 59 (3%) | 1906 (97%) (496, 42) | Gleason pattern 3 (8.3) Gleason pattern 4 (11.4) Gleason pattern 5 (56.1) Nerve (8.6) Blood vessel (6.8) Cribriform pattern (6.9) Normal glandular tissues (1.9) |
HGPIN | 16 (7) | 10× | 204 (2.5) | 8104 (97.5) (581, 35) | Benign Prostatic Hyperplasia (5.8) Gleason pattern 3 (11.4) Gleason pattern 4 (16.2) Gleason pattern 5 (66.6) |
Blood vessel | 96 (18) | 10× | 123 (6.3) | 1820 (93.7) (447,40) | Gleason pattern 3 (9.6) Gleason pattern 4 (10.9) Gleason pattern 5 (57.8) Nerve (8.2) Cribriform pattern (7.9) Normal glandular tissues (2.2) Ductal adenocarcinoma (3.4) |
Nerve | 147 (17) | 10× | 157 (8.0) | 1812 (92.0) (392,41) | Gleason pattern 3 (10.2) Gleason pattern 4 (12.7) Gleason pattern 5 (56.8) Cribriform pattern (6.7) Vessel (6.3) Normal glandular tissues (3.1) Ductal adenocarcinoma (4.2) |
Inflammatory cell infiltration | 109 (22) | 10× | 161 (7.8) | 1904 (92.2) (511, 42) | Gleason pattern 3 (10.0) Gleason pattern 4 (11.4) Gleason pattern 5 (54.1) Nerve. (7.3) Cribriform pattern (6.5) Vessel (5.5) Normal glandular tissues (1.7) Ductal adenocarcinoma (3.5) |
