Table 1 Descriptive summary by number of vaccine dose administered, based on individual measurements.

From: Longitudinal antibody dynamics after COVID-19 vaccine boosters based on prior infection status and booster doses

 

Number of vaccine doses administered

3

4

5

All

(n = 3527)

(n = 2786)

(n = 1063)

(n = 7376)

Sex

 Male

1251 (35.5%)

893 (32.1%)

336 (31.6%)

2480 (33.6%)

 Female

2276 (64.5%)

1893 (67.9%)

727 (68.4%)

4896 (66.4%)

Age group (years)

 18–39

874 (24.8%)

345 (12.4%)

72 (6.8%)

1291 (17.5%)

 40–59

1854 (52.6%)

1093 (39.2%)

280 (26.3%)

3227 (43.8%)

 60–79

597 (16.9%)

960 (34.5%)

535 (50.3%)

2092 (28.4%)

Over 80

202 (5.7%)

388 (13.9%)

176 (16.6%)

766 (10.4%)

Attributes

 General public

1752 (49.7%)

1070 (38.4%)

436 (41.0%)

3258 (44.2%)

 Resident or staff at elder facility

696 (19.7%)

820 (29.4%)

320 (30.1%)

1836 (24.9%)

 Health care professional

1079 (30.6%)

896 (32.2%)

307 (28.9%)

2282 (30.9%)

Underlying medical conditions

 No

2248 (63.7%)

1550 (55.6%)

557 (52.4%)

4355 (59.0%)

 Yes

770 (21.8%)

1018 (36.5%)

474 (44.6%)

2262 (30.7%)

 Missing

509 (14.4%)

218 (7.8%)

32 (3.0%)

759 (10.3%)

Immunocompromised or on immunosuppressant medication

 No

2971 (84.2%)

2513 (90.2%)

1013 (95.3%)

6497 (88.1%)

 Yes

44 (1.2%)

54 (1.9%)

18 (1.7%)

116 (1.6%)

 Missing

512 (14.5%)

219 (7.9%)

32 (3.0%)

763 (10.3%)

Smoking history

 Never-smoker

2408 (68.3%)

2106 (75.6%)

856 (80.5%)

5370 (72.8%)

 Smoker

174 (4.9%)

157 (5.6%)

83 (7.8%)

414 (5.6%)

 Former smoker

449 (12.7%)

312 (11.2%)

98 (9.2%)

859 (11.6%)

 Missing

496 (14.1%)

211 (7.6%)

26 (2.4%)

733 (9.9%)

Alcohol consumption history

 Never-drinker

1885 (53.4%)

1702 (61.1%)

697 (65.6%)

4284 (58.1%)

 Drinker

31 (0.9%)

55 (2.0%)

25 (2.4%)

111 (1.5%)

 Former drinker

1116 (31.6%)

817 (29.3%)

315 (29.6%)

2248 (30.5%)

 Missing

495 (14.0%)

212 (7.6%)

26 (2.4%)

733 (9.9%)

Vaccine type

 BNT162b2

2781 (78.9%)

1329 (48.3%)

3 (0.3%)

4113 (56.1%)

 mRNA1273

715 (20.3%)

830 (30.2%)

0 (0.0%)

1545 (21.1%)

 Omicron-compatible BNT162b2

25 (0.7%)

571 (20.8%)

1024 (96.3%)

1620 (22.1%)

 Omicron-compatible mRNA1273

1 (0.0%)

20 (0.7%)

36 (3.4%)

57 (0.8%)

 Other

3 (0.1%)

0 (0.0%)

0 (0.0%)

3 (0.0%)

Days elapsed since vaccination

188.80 (87.19)

78.90 (54.19)

57.08 (31.70)

128.31 (91.06)

History of COVID-19 infection

 No

2914 (82.6%)

2297 (82.4%)

868 (81.7%)

6079 (82.4%)

 Yes

613 (17.4%)

489 (17.6%)

195 (18.3%)

1297 (17.6%)

Days elapsed since infection

 No history of infection

2914 (82.6%)

2297 (82.4%)

868 (81.7%)

6079 (82.4%)

 0–6 days

2 (0.1%)

0 (0.0%)

1 (0.1%)

3 (0.0%)

 7–89 days

311 (8.8%)

235 (8.4%)

97 (9.1%)

643 (8.7%)

 90–179 days

173 (4.9%)

121 (4.3%)

39 (3.7%)

333 (4.5%)

 Over 180 days

127 (3.6%)

133 (4.8%)

58 (5.5%)

318 (4.3%)

Prevalent strains at infection

 Original strain

18 (1.3%)

20 (2.4%)

7 (3.3%)

45 (1.8%)

 Alpha variant

14 (1.0%)

15 (1.8%)

7 (3.3%)

36 (1.5%)

 Delta variant

4 (0.3%)

9 (1.1%)

3 (1.4%)

16 (0.7%)

 Omicron variant

1360 (97.4%)

800 (94.8%)

198 (92.1%)

2358 (96.0%)

COVID-19 during the study period

 No

2264 (64.2%)

2047 (73.5%)

878 (82.6%)

5189 (70.3%)

 Yes

1263 (35.8%)

739 (26.5%)

185 (17.4%)

2187 (29.7%)

IgG median (interquartile range)

1406.12(4418.49)

4465.91(10,465.83)

7939.61(18,567.65)

2963.59(8674.88)

  1. Total of 7376 data points with 1763 individuals.
  2. Data in the table are No. (%).