Table 3 Adjusted mean intraocular pressure (IOP) difference from preoperative values in XEN63-standalone and XEN63 + Phacoemulsification groups. The model included "Surgery" (XEN63-standalone versus XEN63 + Phaco) as a factor and age, preoperative IOP, preoperative number of ocular hypotensive drugs, pachymetry, and dose of mitomycin-C as covariates.
From: Effectiveness and safety of XEN 63 in patients with primary-open-angle glaucoma
Mean IOP lowering | ||||
|---|---|---|---|---|
XEN63-standalone | XEN63 + Phaco | Difference | pa | |
Day 1 | ||||
N | 42 | 37 | ||
Mean (SE) | −13.8 (1.0) | −12.7 (1.0) | −1.1 (1.5) | 0.4489 |
95% CI | −15.8 to −11.9 | −14.7 to −10.7 | −4.0 to 1.8 | |
Week 1 | ||||
N | 43 | 37 | ||
Mean (SE) | −12.3 (1.0) | −10.9 (1.0) | −1.4 (1.4) | 0.3383 |
95% CI | −14.2 to −10.4 | −12.8 to −8.9 | −4.3 to 1.5 | |
Month 1 | ||||
N | 43 | 37 | ||
Mean (SE) | −7.0 (1.2) | −7.6 (1.3) | 0.6 (1.8) | 0.7124 |
95% CI | −9.3 to −4.6 | −10.1 to −5.1 | −2.9 to 4.3 | |
Month 3 | ||||
N | 41 | 37 | ||
Mean (SE) | −9.3 (0.8) | −7.5 (0.8) | −1.8 (1.2) | 0.1089 |
95% CI | −10.9 to −7.7 | −9.0 to −5.9 | −4.2 to 0.4 | |
Month 6 | ||||
N | 34 | 31 | ||
Mean (SE) | −7.5 (0.8) | −7.7 (0.7) | 0.2 (1.0) | 0.8911 |
95% CI | −9.0 to −6.0 | −9.1 to −6.3 | −1.9 to 2.2 | |
Month 12 | ||||
N | 21 | 23 | ||
Mean (SE) | −7.3 (0.9) | −7.1 (0.8) | −0.2 (1.2) | 0.8759 |
95% CI | −9.0 to −5.5 | −8.7 to −5.4 | −2.7 to 2.3 | |
