Figure 3 | Scientific Reports

Figure 3

From: The human PTGR1 gene expression is controlled by TE-derived Z-DNA forming sequence cooperating with miR-6867-5p

Figure 3

TEs and ZFS in PTGR1 promoter region. (a) Promoter region of the PTGR1 gene (chr9:114,361,574-114,363,508) is represented on the UCSC genome browser. (b) ZFS in the PTGR1 promoter were predicted using Shin's ChIP-Seq data. The read distributions of input, IgG, and three Zaa replicates were visualized using the UCSC genome browser. The region with high Zaa peaks, marked in blue, indicates ZFS. Input and IgG were used as negative controls. c ZHunt analysis was conducted to predict ZFS in the PTGR1 promoter. The z-score indicates a high probability of adopting the Z-DNA conformation. The shaded gray rectangle represents the MER4-int element.

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