Table 1 The characteristics of enrolled subjects with and without HCV Ab seropositivity.

From: Hepatitis C virus antibody seropositivity is associated with albuminuria but not peripheral artery disease in patients with type 2 diabetes

 

HCV Ab ( +) N = 85

HCV Ab (‒) N = 1673

P

Age (years)

69 ± 8

66 ± 9

0.002

Male, n (%)

35 (41.2)

960 (57.4)

0.005

Hypertension, n (%)

69 (81.2)

1312 (78.4)

0.640

CVD history, n (%)

56 (65.9)

1064 (63.6)

0.755

Diabetes duration (years)

12 ± 8

13 ± 8

0.712

BMI (kg/m2)

25.9 ± 4.4

25.9 ± 4.1

0.954

Systolic BP (mm Hg)

139 ± 17

133 ± 18

0.004

Diastolic BP (mm Hg)

75 ± 10

75 ± 11

0.822

Fasting glucose (mmol/L)

7.5 ± 2.2

7.4 ± 2.0

0.677

HbA1c (%)

7.0 ± 1.0

7.0 ± 1.1

0.959

Total cholesterol (mmol/L)

3.9 ± 0.7

3.9 ± 0.8

0.561

LDL cholesterol (mmol/L)

2.1 ± 0.6

2.1 ± 0.7

0.866

HDL cholesterol (mmol/L)

1.4 ± 0.4

1.3 ± 0.4

0.236

Triglycerides (mmol/L)

2.8 ± 1.5

3.2 ± 2.5

0.218

ALT (U/L)

24 ± 17

25 ± 19

0.797

eGFR (mL/min/1.73 m2)

68 ± 20

73 ± 22

0.034

UACR (mg/g)

274 ± 611

123 ± 433

0.002

ABI

1.1 ± 0.1

1.1 ± 0.1

0.461

Use of antiplatelet drugs, n (%)

19 (22.4)

431 (25.8)

0.565

Use of statins, n (%)

64 (75.3)

1364 (81.5)

0.196

Use of antihypertensive drugs, n (%)

49 (57.6)

842 (50.3)

0.228

Use of ACE inhibitors or ARBs, n (%)

33 (38.8)

592 (35.4)

0.596

Insulin therapy, n (%)

25 (29.4)

325 (19.4)

0.035

Oral antihyperglycemic drugs, n (%)

78 (91.8)

1596 (95.4)

0.204

Insulin secretagogues, n (%)

24 (28.2)

528 (31.6)

0.600

Metformin, n (%)

29 (34.1)

634 (37.9)

0.558

DPP4 inhibitors, n (%)

44 (51.8)

844 (50.4)

0.900

SGLT2 inhibitors, n (%)

26 (30.6)

527 (31.5)

0.955

Thiazolidinediones, n (%)

26 (30.6)

593 (35.4)

0.425

α-Glucosidase inhibitors, n (%)

8 (9.4)

82 (4.9)

0.112

  1. ABI ankle-brachial index, ACE angiotensin-converting enzyme, ALT alanine aminotransferase, ARB angiotensin II receptor antagonist, BMI body mass index, BP blood pressure, CVD cardiovascular disease, DPP4 dipeptidyl peptidase-4, eGFR estimated glomerular filtration rate, HbA1c glycated hemoglobin, HDL high-density lipoprotein, HCV Ab anti-hepatitis C virus antibody, LDL low-density lipoprotein, SGLT2 sodium-glucose cotransporter 2, UACR urinary albumin-to-creatinine ratio.