Table 2 Descriptive analysis and comparison of hand OA patients according to EHOA.

From: Metabolic syndrome is not associated with erosive hand osteoarthritis: a cross-sectional study using data from the PROCOAC cohort

 

Erosive

(n = 303)

Non-erosive

(n = 736)

  

Mean (SD)

Mean (SD)

OR (95%CI)

p

Age at diagnosis

59 (8.17)

65 (8.97)

0.93 (0.92–0.95)

< 0.001

BMI

30 (12.96)

29 (24.61)

1.00 (0.98–1.01)

0.653

Abdominal perimeter (cm)

93 (12.71)

96 (11.98)

0.98 (0.97–0.99)

0.002

Total AUSCAN

54 (26.92)

41 (29.50)

1.02 (1.01–1.02)

< 0.001

Pain AUSCAN

56 (27.81)

43 (31.85)

1.01 (1.01–1.02)

< 0.001

Stiffness AUSCAN

54 (32.88)

39 (36.00)

1.01 (1.01–1.02)

< 0.001

Function AUSCAN

54 (28.44)

40 (30.28)

1.02 (1.01–1.02)

< 0.001

ESR

20 (13.41)

19 (14.91)

1 (0.99–1.01)

0.408

CRP (mg/dL)

0 (0.54)

0 (1.01)

0.95 (0.75–1.12)

0.597

 

n (%)

n (%)

  

Sex

 Male

38 (12.54)

143 (19.43)

0.6 (0.40–0.87)

0.009

 Female

265 (87.46)

593 (80.57)

1.00

 

Hypertension

114 (37.75)

385 (52.52)

0.55 (0.41–0.72)

< 0.001

Diabetes

57 (18.87)

129 (17.67)

1.09 (0.76–1.53)

0.641

Dyslipidemia

168 (55.45)

431 (58.72)

0.88 (0.67–1.15)

0.344

Hypertriglyceridemia

47 (15.72)

121 (17.26)

1.09 (0,76–1.53)

0.550

Low HDL

30 (9.97)

65 (9.25)

0.88 (0.67–1.15)

0.344

MetS

50 (16.50)

152 (20.82)

0.75 (0.53–1.07)

0.114

Osteoporosis

44 (14.52)

122 (16.58)

1.33 (0.93–1.88)

0.116

Osteopenia

30 (9.90)

77 (10.46)

0.86 (0.58–1.24)

0.417

Smoking habit

    

 Never

177 (58.42)

482 (65.94)

1.00

 

 Current

39 (12.87)

83 (11.35)

1.28 (0.84–1.94)

0.243

 Former

87 (28.71)

166 (22.71)

1.43 (1.05–1.95)

0.024

Psoriasis

21 (6.93)

66 (9.02)

0.9 (0.62–1.29)

0.557

Knee OA (KL > I)

155 (53.26)

558 (77.50)

0.33 (0.25–0.44)

< 0.001

Hip OA

109 (37.33)

406 (57.43)

0.44 (0.33–0.58)

< 0.001

Inflammatory hand OA

80 (26.49)

37 (5.08)

6.74 (4.44–10.24)

< 0.001

Nodular hand OA

290 (96.03)

566 (78.72)

6.53 (3.57–11.95)

< 0.001

Thumb base OA

160 (53.16)

489 (67.45)

0.55 (0.42–0.72)

< 0.001

Positive RF

24 (8.42)

57 (8.77)

0.96 (0.58–1.57)

0.856

Positive ACPA

3 (1.11)

9 (1.52)

0.72 (0.19–2070)

0.630

  1. BMI, body mass index (Kg/m2); HDL, high-density lipoprotein; MetS, metabolic syndrome; Knee OA, OA at least in one knee; Hip OA, OA at least in one hip; EHOA, erosive hand osteoarthritis at least in one hand; Inflammatory hand OA, OA at least in one hand; Nodular hand OA, OA at least in one hand; Thumb base OA, OA at least in one hand; ESR, erythrocyte sedimentation rate (mmHg); CRP, C-reactive protein (mg/dL); RF, rheumatoid factor; ACPA, anti-citrullinated protein antibodies.
  2. Significant values are in [bold].
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