Figure 2 | Scientific Reports

Figure 2

From: Assessing the fate and contribution of Foxd1-expressing embryonic precursors and their progeny in palatal development, homeostasis and excisional repair

Figure 2

Foxd1-positive progenitor cells and their progeny contribute to vascular cell populations within the developing secondary palate. (A) To characterize the differentiated populations represented by the Foxd1 lineage, the constitutively active Foxd1GC line crossed to the Ai14 reporter was assessed. Tissues were counterstained for CD31, CD146 and CD105 to detect developing vasculature within the palatal tissues from E12.5 to E17.5. Scale bar: 200 μm. (B–D) Schematic representation of murine orofacial tissues at E12.5–E17.5 are shown at each stage, highlighting the regions (black dashed box) that contribute to secondary palate development (palatal processes/shelves). Scale bar: 200 μm. White arrowheads indicate areas with overlapping signal. PS palatal shelve, NS nasal septum. Separate channel images are shown in supplemental file 2.

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