Figure 7 | Scientific Reports

Figure 7

From: Cysteine protease inhibitor 1 promotes metastasis by mediating an oxidative phosphorylation/MEK/ERK axis in esophageal squamous carcinoma cancer

Figure 7

Interaction between OXPHOS and MEK/ERK pathway. (A) Changes of MEK/ERK pathway after the addition of Rotenone (2 μM, the complex I enzyme inhibitor). (B) Changes of complex I enzyme activity after the addition of PD98059 (20 μM, MEK/ERK pathway inhibitor). (C) Changes of cellular ATP production after addition of PD98059 (20 μM, MEK/ERK pathway inhibitor). (* P < 0.05,** P < 0.01,*** P < 0.001).

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