Figure 5 | Scientific Reports

Figure 5

From: High biocompatible FITC-conjugated silica nanoparticles for cell labeling in both in vitro and in vivo models

Figure 5The alternative text for this image may have been generated using AI.

Analysis of fluorescence signals of FITC-SiO2-COOH NPs. (a) The uptake of FITC-SiO2-COOH NPs and a commercial fluorescence kit in the hUVECs after different times of incubation. (b) The quantitative comparison of fluorescence signals at different time points of hUVECs and a commercial kit. (c) hFBs and HeLa cells incubated with FITC-SiO2-COOH NPs at various times. (d) The intracellular distribution of FITC-SiO2-COOH NPs in hFBs. The relative localization of FITC-SiO2-COOH NPs (green) in the cytoplasm and CD63 membrane protein (red, left), or alpha-tubulin (red, right). (e) Quantitative comparison of fluorescence signals at different time points at 50 µg/mL and 100 µg/mL NPs in hFBs and HeLa cells. Data was collected from three biological trials (n = 3) and presented as mean ± SD. *p < 0.05; **p < 0.01; ***p < 0.001.

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