Figure 1

Study design depicting allocation of dogs to groups and their duration of treatment. Canine patients were divided into vehicle treatment group (n = 11) and netarsudil treatment group (n = 10). Of the 11 dogs enrolled in the vehicle treatment group, 2 dogs were treated for 4 months with vehicle only, 5 dogs were treated for 4 months with vehicle then 4 months with netarsudil, and 4 dogs were treated for 4 months with vehicle then 8 months with netarsudil. Of the 10 dogs enrolled in the netarsudil treatment group, 1, 4 and 5 dogs were treated for 4, 8 and 5 months, respectively.