Figure 3
From: Topical netarsudil for the treatment of primary corneal endothelial degeneration in dogs

No significant differences were observed in IOP (A) or STT-1 values (B) between the netarsudil (10 dogs, 12 eyes) and vehicle control (11 dogs, 14 eyes) groups or baseline and any timepoints. Box plots depict median, and 25th and 75th percentiles. Whisker plots show maximum and minimum values. Two-way repeated measures ANOVA was performed. No differences in STT or IOP were observed between netarsudil and vehicle control groups at any timepoint or in comparison to baseline, P > 0.05. IOP: intraocular pressure as measured by rebound tonometry. STT: Schirmer tear test. Netarsudil group: baseline, 1, 2 and 4 months: 12 eyes; Six and 8 months: 11 eyes; 12 months: 6 eyes. Vehicle group: baseline, 1, 2 and 4 months: 14 eyes; 6 months: 13 eyes; 8 months: 12 eyes; 12 months: 5 eyes.