Figure 4 | Scientific Reports

Figure 4

From: Topical netarsudil for the treatment of primary corneal endothelial degeneration in dogs

Figure 4

No significant differences were observed in CCT measured by USP (A), corneal stromal thickness measured by OCT (B), ECD measured with non-applanation IVCM (C), and percentage of cornea affected by edema (D) in patients treated with netarsudil during 8 months versus patients receiving vehicle control during the first 4 months. Two-way repeated measures ANOVA. Depicted are the mean and the standard deviation. For CCT, USP, percentage of corneal edema: Netarsudil group: baseline, 1, 2 and 4 months: 12 eyes. Six months and 8 months: 11 eyes. Twelve months: 6 eyes. Vehicle group: baseline, 1, 2 and 4 months: 14 eyes. Six months: 13 eyes. Eight months: 12 eyes. Twelve months: 5 eyes. ECD: Netarsudil group: baseline, 1, 2 and 4 months: 12 eyes. Six and 8 months: 11 eyes. Twelve months: 5 eyes. Vehicle group: baseline, 1, 2 and 4 months: 14 eyes. Six months: 13 eyes. Eight months: 12 eyes. Twelve months: 3 eyes.

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