Figure 7
From: Topical netarsudil for the treatment of primary corneal endothelial degeneration in dogs
Kaplan Meier curves demonstrate no significant difference in clinical progression using multiple criteria (A) or corneal edema progression (B) in canine PCED patients treated with netarsudil or vehicle control for the initial 4 months. Using the combined clinical criteria (A) or only corneal edema progression (B), no statistical differences were observed between patients treated with netarsudil and patients treated with vehicle control during the first 4 months (A, P = 0.84; B, P = 0.08). For the Kaplan Meier curves, progression was established using combined clinical criteria (A, progressed if eyes demonstrated a > 10% decrease in ECD, a > 10% increase of cornea affected by edema, and/or a > 20% increase in CCT) and corneal edema progression alone (B, when the eye had an increase of > 10% in area of the cornea affected by edema).
