Figure 6
From: A novel multidrug-resistant cell line from a Chinese patient with pancreatic ductal adenocarcinoma
Hematoxylin–eosin (H&E) staining of the primary tumour, PDAC-X2 cells and xenografted tumour. The primary tumour showed moderately to poorly differentiated PDAC cells, with the tumour cells arranged in an irregular glandular tubular, cord-like and nest-like pattern, with abundant stromal components around the tumour (A). PDAC-X2 cells were significant differences in size. The nucleus was enlarged, the nucleolus was obvious and the cytoplasm was few. Multiple multinucleated (red arrow) and megakaryocytes (green arrow) were visible, presenting typical malignant tumour cell manifestations (B). The transplanted tumour showed irregular glandular-like cell structures, exhibiting moderate to low differentiation, and its histological morphology was similar to that of the primary tumour (C). (scale bar = 50 μm)
