Table 1 Data used for the Mendelian randomization analysis.

From: Genetic correlations and causal relationships between cardio-metabolic traits and sepsis

ID

Trait

Population

Sex

Category

Sample_size

nsnp

ncontrol

ncase

pmid

ieu-b-35

C-Reactive protein level

European

Males and females

Continuous

204,402

2,414,379

NA

NA

30,388,399

ebi-a-GCST005195

Coronary artery disease

NA

NA

NA

547,261

7,934,254

424,528

122,733

29,212,778

ieu-b-109

HDL cholesterol

European

Males and females

Continuous

403,943

12,321,875

NA

NA

32,203,549

ebi-a-GCST90002412

Low density lipoprotein cholesterol levels

European

NA

NA

431,167

16,293,344

NA

NA

32,493,714

ieu-b-4980

Sepsis

European

Males and females

Disease

486,484

12,243,539

474,841

11,643

NA

ieu-b-5066

Sepsis (under 75)

European

Males and females

Disease

462,869

12,243,540

451,301

11,568

NA

ieu-a-301

Total cholesterol

Mixed

Males and females

Risk factor

187,365

2,446,982

NA

NA

24,097,068

ebi-a-GCST006867

Type 2 diabetes

European

NA

NA

655,666

5,030,727

1178

61,714

30,054,458

ieu-b-29

Basophil cell count

European

Males and females

Continuous

563,946

NA

NA

NA

NA

ieu-b-40

Body mass index

European

Males and females

Continuous

681,275

2,336,260

NA

NA

30,124,842

ieu-b-39

Diastolic blood pressure

European

Males and females

Continuous

757,601

7,160,619

NA

NA

30,224,653

ieu-b-33

Eosinophil cell count

European

Males and females

Continuous

563,946

NA

NA

NA

NA

ieu-b-32

Lymphocyte cell count

European

Males and females

Continuous

563,946

NA

NA

NA

NA

ieu-b-31

Monocyte cell count

European

Males and females

Continuous

563,946

NA

NA

NA

NA

ieu-b-34

Neutrophil cell count

European

Males and females

Continuous

563,946

NA

NA

NA

NA

ieu-b-38

Systolic blood pressure

European

Males and females

Continuous

757,601

7,088,083

NA

NA

30,224,653

ieu-b-111

Triglycerides

European

Males and females

Continuous

441,016

12,321,875

NA

NA

32,203,549

ieu-b-30

White blood cell count

European

Males and females

Continuous

563,946

NA

NA

NA

NA

  1. For categorical outcome data participant numbers were split into cases and controls.