Table 4 Overview of the top 10 KEGG pathways.
From: Identification of key autophagy-related genes and pathways in spinal cord injury
Term | Count | % | P value | Genes |
|---|---|---|---|---|
Salmonella infection | 24 | 18.60465 | 6.94E−15 | MLKL, ANXA2, RIPK3, TNFRSF10B, TNF, PIK3CG, TNFRSF1A, TUBA1C, IL6, TUBB6, CASP7, CASP8, MYC, IL1B, CASP4, CASP1, FLNA, RIPK1, FLNC, PFN1, TLR4, TUBA8, BIRC3, TLR2 |
TNF signaling pathway | 17 | 13.17829 | 1.34E−13 | CEBPB, MLKL, RIPK3, TNFAIP3, NOD2, PTGS2, TNF, TNFRSF1A, IL6, MMP14, CASP7, CASP8, IL1B, CCL2, FAS, RIPK1, BIRC3 |
Apoptosis | 18 | 13.95349 | 1.79E−13 | APAF1, TNFRSF10B, NGF, TNF, CTSS, LMNB1, TNFRSF1A, TUBA1C, CASP7, CASP8, CTSL, PMAIP1, FAS, BIRC5, RIPK1, CTSD, TUBA8, BIRC3 |
p53 signaling pathway | 14 | 10.85271 | 1.21E−12 | CDKN1A, APAF1, CDKN2A, IGFBP3, SERPINE1, TNFRSF10B, IGF1, THBS1, CASP8, CDK6, CHEK1, CDK1, PMAIP1, FAS |
Proteoglycans in cancer | 17 | 13.17829 | 1.31E−09 | CDKN1A, TGFB1, HGF, FN1, IGF1, THBS1, TNF, CTSL, MYC, FLNA, FAS, ITGAV, ITGA5, FLNC, TLR4, CD44, TLR2 |
Malaria | 10 | 7.751938 | 1.45E−08 | IL6, TGFB1, IL1B, HGF, ITGB2, CCL2, THBS1, TNF, TLR4, TLR2 |
Tuberculosis | 15 | 11.62791 | 1.61E−08 | CEBPB, TGFB1, APAF1, SPHK1, ITGB2, NOD2, TNF, CTSS, TNFRSF1A, IL6, CASP8, IL1B, CTSD, TLR4, TLR2 |
Chagas disease | 12 | 9.302326 | 2.34E−08 | IL6, CASP8, TGFB1, IL1B, SERPINE1, FAS, CCL2, TNF, TLR4, TNFRSF1A, TGFBR2, TLR2 |
Legionellosis | 10 | 7.751938 | 2.70E−08 | IL6, CASP7, CASP8, APAF1, IL1B, ITGB2, CASP1, TNF, TLR4, TLR2 |
Human cytomegalovirus infection | 17 | 13.17829 | 3.20E−08 | CDKN1A, CDKN2A, CXCR4, PTGS2, TNF, TNFRSF1A, IL6, CASP8, CDK6, MYC, IL1B, EIF4EBP1, CCL2, FAS, RIPK1, ITGAV, CCR5 |
