Table 2 The target metabolic pathways to PDAC.

From: Metabolic responses to the occurrence and chemotherapy of pancreatic cancer: biomarker identification and prognosis prediction

Pathway name

Hits

P

 − log(P)

Holm P

Impact

Alanine, aspartate and glutamate metabolism

6/28

5.4 × 10–8

7.3

4.5 × 10–6

0.53

Arginine biosynthesis

3/14

2.0 × 10–4

3.7

1.6 × 10–2

0.12

Histidine metabolism

3/16

3.1 × 10–4

3.5

2.4 × 10–2

0.22

d-Glutamine and d-glutamate metabolism

2/6

1.1 × 10–3

3.0

8.7 × 10–2

0.50

Citrate cycle

2/20

1.3 × 10–2

1.9

1.0 × 100

0.14

Pyruvate metabolism

2/22

1.5 × 10–2

1.8

1.0 × 100

0.21

glycolysis/gluconeogenesis

2/26

2.2 × 10–2

1.7

1.0 × 100

0.10