Figure 2

Induced MOG-reactive CD4⁺CD25^highCD127^low regulatory T cells (Tregs) ameliorated experimental autoimmune encephalomyelitis (EAE) symptoms. Changes in (A) disease severity scores and (B) body weight was observed in the wild-type (WT) (n = 14), sham-treated EAE (n = 20), and Treg-treated EAE groups (n = 14). All the data are presented as the median and interquartile range. *P < 0.05, **P < 0.01.