Figure 2

Serum concentrations of LPS molecules (A) and FITC-dextran (B) after IMO stress in a mouse model of AD. In vivo fluorescence images (C) and a bar graph (D) showing the time-dependent distribution of Cy5.5-labeled bacterial LPS surgically injected into the colon after IMO stress in TMA-treated mice. Nude male mice on a BALB/c background were used for the in vivo immunofluorescence study. ##p < 0·01, ###p < 0·001 versus NOR group; *p < 0·05, ***p < 0·001 versus TMA group. LPS, lipopolysaccharides; FITC, fluorescein isothiocyanate; AD, atopic dermatitis; IMO, immobilization; TMA, trimellitic anhydride; NOR, normal.