Figure 2
From: Alteration in kynurenine pathway metabolites in young women with autoimmune thyroiditis
The activity of kynurenine pathway enzymes in controls (CON) and young women with autoimmune thyroiditis (AIT). The activity of individual KP enzymes were calculated indirectly, by the determination of product/substrate ratios, (a) IDO1, TDO activity (KYN/TRP ratio), (b) KAT activity (KYNA/KYN ratio), (c) KYNU A activity (AA/KYN ratio), (d) KMO activity (3-HKYN/KYN ratio), (e) A3H activity (3HAA/AA ratio), (f) 3-HAAO activity (QA/3-HAA ratio). *p < 0.05; **p < 0.01; ***p < 0.001 controls versus AIT.
