Figure 2

CRRGPI construction and validation. (A) LASSO coefficients of prognostic gene sets. (B) Threefold cross-validation for the selection of prognostic gene sets in LASSO regression. CRRGPI was constructed based on LASSO regression analysis and validated in the training cohort (C), whole TCGA cohort (D), test cohort (E), and GSE65858 cohort (F). CRRGPI, Circadian Rhythm-Related Gene Prognostic Index.