Table 1 Comparison of clinical features between the HTN group and non-HTN group, as well as between the training set and validation set.

From: Development of hypertension models for lung cancer screening cohorts using clinical and thoracic aorta imaging factors

Features

Non-HTN (n = 365)

HTN (n = 439)

Statistic value

P value

Training set (n = 562)

Validation set (n = 242)

Statistic value

P value

Age

52.00 (45.00, 59.30)

52.00 (51.00, 70.00)

− 8.498

 < 0.001

55.00 (49.00, 66.00)

55.00 (47.95, 62.00)

− 1.291

0.197

Sex (male%)

150 (41.10%)

96 (21.87%)

34.699

 < 0.001

170 (30.25%)

76 (31.40%)

0.106

0.744

Height

167.00 (160.00, 172.00)

167.00 (164.20, 174.00)

− 3.003

0.003

168.00 (163.00, 173.00)

168.00 (162.00, 172.00)

− 0.596

0.551

Weight

64.70 (56.40, 73.00)

64.70 (64.62, 79.00)

− 8.168

 < 0.001

69.80 (60.20, 76.51)

69.80 (60.58, 77.71)

0.25

0.802

BMI

23.00 (21.37, 25.30)

23.00 (23.42, 27.10)

− 9.452

 < 0.001

24.25 (22.30, 26.50)

24.25 (22.30, 26.60)

0.289

0.773

GLU

4.78 (4.45, 5.20)

4.78 (4.73, 5.80)

− 7.265

 < 0.001

4.96 (4.59, 5.60)

4.96 (4.64, 5.50)

− 0.063

0.95

CHOL

4.52 (3.94, 5.26)

4.52 (3.51, 5.08)

3.723

 < 0.001

4.51 (3.67, 5.15)

4.51 (3.79, 5.19)

1.244

0.214

TG

1.12 (0.87, 1.57)

1.12 (1.10, 2.56)

− 8.062

 < 0.001

1.36 (0.98, 2.08)

1.36 (0.99, 2.17)

0.074

0.941

HDL.C

1.26 (1.07, 1.54)

1.26 (0.92, 1.26)

8.414

 < 0.001

1.16 (0.96, 1.38)

1.16 (0.99, 1.42)

0.972

0.331

LDL.C

2.78 (2.29, 3.33)

2.78 (1.86, 3.16)

4.3

 < 0.001

2.75 (2.02, 3.23)

2.75 (2.15, 3.32)

1.192

0.233

ALT

20.00 (14.00, 29.00)

20.00 (16.00, 32.00)

− 3.202

0.001

22.00 (15.00, 31.00)

22.00 (15.00, 31.00)

0.287

0.774

AST

20.00 (17.00, 25.00)

20.00 (18.00, 26.00)

− 1.691

0.091

21.00 (17.95, 25.00)

21.00 (18.00, 25.00)

0.057

0.955

BUN

4.94 (4.18, 5.70)

4.94 (4.49, 6.35)

− 4.197

 < 0.001

5.12 (4.29, 6.08)

5.12 (4.35, 5.85)

− 0.867

0.386

CREA

68.30 (58.50, 77.26)

68.30 (65.88, 85.28)

− 7.187

 < 0.001

71.40 (62.10, 82.20)

71.40 (62.09, 80.53)

− 0.713

0.476

Na

140.60 (139.37, 141.60)

140.60 (139.50, 141.88)

− 0.977

0.328

140.60 (139.40, 141.80)

140.60 (139.50, 141.60)

− 0.209

0.835

K

3.97 (3.81, 4.13)

3.97 (3.71, 4.11)

3.232

0.001

3.96 (3.75, 4.12)

3.96 (3.80, 4.12)

1.161

0.246

Ca

2.23 (2.16, 2.31)

2.23 (2.15, 2.31)

0.597

0.55

2.22 (2.15, 2.32)

2.22 (2.15, 2.30)

− 0.973

0.331

Mg

0.87 (0.83, 0.92)

0.87 (0.82, 0.93)

0.103

0.918

0.88 (0.82, 0.92)

0.88 (0.83, 0.92)

0.833

0.405

CL

102.40 (101.00, 103.60)

102.40 (100.50, 103.78)

1.51

0.131

102.20 (100.80, 103.70)

102.20 (100.70, 103.50)

− 0.386

0.699

PHOS

1.01 (0.93, 1.12)

1.01 (0.90, 1.10)

1.433

0.152

1.02 (0.91, 1.11)

1.02 (0.91, 1.11)

0.45

0.653

CO2

25.60 (24.20, 27.03)

25.60 (23.72, 26.90)

1.337

0.181

25.40 (24.10, 27.00)

25.40 (23.80, 26.81)

− 1.533

0.125

Hypergly

77 (21.10%)

210 (47.83%)

62.96

 < 0.001

203 (36.12%)

84 (34.71%)

5.777

0.056

Hyperuri

49 (13.42%)

126 (28.70%)

27.315

 < 0.001

131 (23.31%)

44 (18.18%)

2.612

0.106

Hyperlip

135 (36.99%)

223 (50.80%)

15.39

 < 0.001

248 (44.13%)

110 (45.45%)

0.12

0.729

Peri_AS

235 (64.38%)

391 (89.07%)

70.436

 < 0.001

442 (78.65%)

184 (76.03%)

0.671

0.413

Con_AS

92 (25.21%)

216 (49.20%)

48.563

 < 0.001

217 (38.61%)

91 (37.60%)

0.073

0.787

CHD

34 (9.32%)

108 (24.60%)

32.024

 < 0.001

107 (19.04%)

35 (14.46%)

2.436

0.119

Cere_AS

47 (12.88%)

126 (28.70%)

29.554

 < 0.001

125 (22.24%)

48 (19.83%)

0.58

0.446

Lacunar infarction

127 (34.79%)

244 (55.58%)

34.65

 < 0.001

271 (48.22%)

100 (41.32%)

3.239

0.072

OP

56 (15.34%)

74 (16.86%)

0.337

0.562

92 (16.37%)

38 (15.70%)

0.056

0.814

CKD

360 (98.63%)

401 (91.34%)

20.901

 < 0.001

533 (94.84%)

228 (94.21%)

0.131

0.718

COPD

5 (1.37%)

20 (4.56%)

6.714

0.01

19 (3.38%)

6 (2.48%)

0.456

0.499

Fatty liver

125 (34.25%)

241 (54.90%)

34.272

 < 0.001

249 (44.31%)

117 (48.35%)

1.114

0.291

Smoking

104 (28.49%)

165 (37.59%)

7.4

0.007

188 (33.45%)

81 (33.47%)

0

0.996

Drinking

88 (24.11%)

143 (32.57%)

6.973

0.008

162 (28.83%)

69 (28.51%)

0.008

0.928

  1. Non-HTN non-Hypertension; HTN Hypertension; BMI body mass index; GLU fasting blood glucose; CHOL Cholesterol; TG Triglyceride; HDL.C high-density lipoprotein cholesterol; LDL.C low-density lipoprotein cholesterol; ALT alanine aminotransferase; AST aspartate aminotransferase; BUN blood urea nitrogen; CREA creatinine; Na serum sodium; K serum potassium; Ca serum calcium; Mg serum magnesium; CL serum chlorine; PHOS serum phosphorus; CO2 carbon dioxide; Hypergly Hyperglycemia; Hyperuri Hyperuricemia; Hyperlip Hyperlipidemia; Peri_AS peripheral arteriosclerosis; Con_AS coronary arteriosclerosis; CHD coronary heart disease; Cere_AS cerebral arteriosclerosis; OP osteoporosis; CKD chronic kidney disease; COPD chronic obstructive pulmonary disease.
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