Table 2 Demographic characteristics of eligible All of Us Research Program participants.

From: Measuring social determinants of health in the All of Us Research Program

 

SDOH survey respondentsa (n = 117,783)

SDOH survey non-respondentsa (n = 279,949)

Difference between respondents and non-respondents (95% CI)

Age, years, Mean (Standard deviation)

59.3 (16.5)

53.1 (17.0)

6.2 (6.1, 6.3)

Characteristic

N (%)

N (%)

 

 RBR Overall

25,483 (21.6%)

39,263 (14.0%)

7.6% (7.3%, 7.9%)

 UBR Overall

92,300 (78.4%)

240,686 (86.0%)

− 7.6% (− 7.9%, − 7.3%)

Racial Identityb

 White

87,886 (74.6%)

125,452 (44.8%)

26.6% (26.3%, 26.9%)

 Black, African or African American

8984 (7.6%)

65,958 (23.6%)

− 16.0% (− 16.2%, − 15.8%)

 Hispanic/Latino/Spanish

7980 (6.8%)

54,776 (19.6%)

− 12.8% (− 13.0%, − 12.6%)

 Asian

3117 (2.6%)

9,982 (3.6%)

− 1.0% (− 1.1%, − 0.9%)

 Native Hawaiian or Pacific Islander

57 (0%)

346 (0.1%)

− 0.1% (− 0.1%, − 0.1%)

 Middle Eastern or North African

467 (0.4%)

1760 (0.6%)

− 0.2% (− 0.3%, − 0.2%)

 Multi-Racial

4221 (3.6%)

11,332 (4.0%)

− 0.4% (− 0.5%, − 0.3%)

 None of these describe me

1039 (0.9%)

3148 (1.15%)

− 0.3% (− 0.3%, − 0.2%)

 Prefer not to answer or skip

4032 (3.4%)

7195 (2.6%)

0.8% (0.7%, 0.9%)

Sex assigned at birth

 Female

74,451 (63.2%)

165,071 (59.0%)

4.2% (3.9%, 4.5%)

 Male

40,354 (34.3%)

109,494 (39.1%)

− 4.8% (− 5.1%, − 4.5%)

 Intersex, none of these describe me, prefer not to answer, or skip

2978 (2.5%)

5384 (1.9%)

0.6% (0.5%, 0.7%)

Gender identity

 Woman

73,499 (62.4%)

164,032 (58.6%)

3.8% (3.5%, 4.1%)

 Man

40,013 (34%)

108,950 (38.9%)

− 4.9% (− 5.2%, − 4.6%)

 Non-Binary

522 (0.4%)

613 (0.2%)

0.2% (0.2%, 0.2%)

 Transgender

171 (0.1%)

365 (0.1%)

0.0% (0.0%, 0.0%)

 None of these describe me, prefer not to answer, or skip

3578 (3%)

5989 (2.1%)

0.9% (0.8%, 1.0%)

Sexual orientation

 Straight

101,913 (86.5%)

244,515 (87.3%)

− 0.8% (− 1.0%, − 0.6%)

 Lesbian

1699 (1.4%)

3213 (1.1%)

0.4% (0.3%, 0.5%)

 Gay

3061 (2.6%)

5990 (2.1%)

0.5% (0.4%, 0.6%)

 Bisexual

4650 (3.9%)

9771 (3.5%)

0.4% (0.3%, 0.5%)

 None of these describe me

2343 (2%)

5948 (2.1%)

− 0.1% (− 0.2%, 0.0%)

 Multiple

364 (0.3%)

338 (0.1%)

0.2% (0.2%, 0.2%)

 Prefer not to answer or skip

3753 (3.2%)

10,174 (3.6%)

− 0.4% (− 0.5%, − 0.3%)

Educational attainment

 College graduate or advanced degree

73,606 (62.5%)

100,892 (36.0%)

26.5% (26.2%, 26.8%)

 College (Years One to Three)

27,446 (23.3%)

72,400 (25.9%)

− 2.6% (− 2.9%, − 2.3%)

 Grade Twelve or GED

10,694 (9.1%)

63,959 (22.8%)

− 13.7% (− 13.9%, − 13.5%)

 Less than high school degree or equivalent

2585 (2.2%)

33,136 (11.8%)

− 9.6% (− 9.7%, − 9.5%)

 Prefer not to answer or skip

3452 (2.9%)

9562 (3.4%)

− 0.5% (− 0.6%, − 0.4%)

Annual household income

 > 150 k

21,212 (18%)

23,240 (8.3%)

9.7% (9.5%, 9.9%)

 100–150 k

18,655 (15.8%)

21,248 (7.6%)

8.2% (8.0%, 8.4%)

 50–100 k

30,963 (26.3%)

43,118 (15.4%)

10.9% (10.6%, 11.2%)

 < 50 k

32,700 (27.8%)

125,917 (45.0%)

− 17.2% (− 17.5%, − 16.9%)

 Prefer not to answer or skip

14,253 (12.1%)

66,426 (23.7%)

− 11.6% (− 11.8%, − 11.4%)

Disability

 No disabilities identified

51,964 (44.1%)

59,275 (21.2%)

20.9% (20.6%, 21.2%)

 Living with disabilities

15,659 (13.3%)

25,598 (9.1%)

4.2% (4.0%, 4.4%)

 Not assessedc

50,160 (42.6%)

195,076 (69.7%)

− 27.1% (− 27.4%, − 26.8%)

Survey language

 English

115,196 (97.8%)

258,827 (92.5%)

5.3% (5.2%, 5.4%)

 Spanish

2587 (2.2%)

21,122 (7.5%)

− 5.3% (− 5.4%, − 5.2%)

  1. RBR represented in biomedical research; UBR underrepresented in biomedical research.
  2. aRespondents or non-respondents, respectively, are defined as those with or without any responses to the SDOH survey as of June 30, 2022 in the All of Us Research Program Version 7 data release. All of Us participants who completed core baseline surveys were eligible to take the SDOH survey.
  3. bFull racial and ethnic identity data (e.g., Japanese, Cuban) not provided due to space limitation.
  4. cParticipants who responded to the core Basics survey before October 22, 2019 were not surveyed for demographic information on disability.