Table 3 Odds ratio (95% confidence interval) of patients with COVID-19 hospitalization based on genotypes of different single nucleotide polymorphisms of vitamin D receptors.

From: Comparing vitamin D receptor gene polymorphisms in rs11568820, rs7970314, rs4334089 between COVID-19 patients with mild and severe symptoms: a case control study

SNPs

Models

Genotype

Crude model

Adjusted model*

OR (95% CI)

P value

OR (95% CI)

P value

rs11568820

Genotypic

CT versus CC

1.44 (0.76, 2.72)

0.262

1.76 (0.85, 3.66)

0.129

TT versus CC

0.20 (0.05, 0.74)

0.016

0.18 (0.04, 0.88)

0.034

Dominant

T versus CC

1.00 (0.55, 1.08)

0.996

1.14 (0.58, 2.25)

0.686

Recessive

TT versus C

0.17 (0.05, 0.61)

0.007

0.14 (0.31, 0.67)

0.014

rs7970314

Genotypic

AG versus AA

1.17 (0.61, 2.25)

0.626

1.04 (0.49, 2.21)

0.912

GG versus AA

0.51 (0.21, 1.25)

0.143

0.63 (0.24, 1.65)

0.346

Dominant

G versus AA

0.93 (0.51, 1.71)

0.827

0.89 (0.44, 1.78)

0.746

Recessive

GG versus A

0.47 (0.21, 1.08)

0.076

0.61 (0.25, 1.49)

0.282

rs4334089

Genotypic

CT versus CC

0.86 (0.45, 1.65)

0.654

0.74 (0.34, 1.58)

0.432

TT versus CC

1.02 (0.40, 2.58)

0.965

0.92 (0.300, 2.82)

0.886

Dominant

T versus CC

0.90 (0.50, 1.63)

0.735

0.78 (0.39, 1.57)

0.485

Recessive

TT versus C

1.08 (0.44, 2.64)

0.864

1.03 (0.35, 3.05)

0.947

  1. SNP single nucleotide polymorphism, OR (95% CI) odds ratio (95% confidence interval).
  2. *Adjusted for comorbidities including coronary heart disease (yes/no), current smoker (yes/no); body mass index (kg/m2).
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