Figure 3

Construction of a prognostic risk model for paediatric MB. (A) The coefficient profiles of 21 MRGs based on the LASSO algorithm. (B) The selection of the optimal parameter (lambda) based on Ten-time cross-validation. (C) The time-dependent ROC curves of OS time based on the GSE85217 paediatric MB cohort. (D) The distributions of risk score, OS, and survival status in the GSE85217 paediatric MB cohort. (E) The heatmap shows the relationship between the risk score and the expression of 12 MRGs in this risk model. (F) K‒M curves of OS in high-risk and low-risk patients.