Table 10 Cardiac toxicity of the identified metabolites using Pred-hERG web server.
Metabolite number | Prediction/potency | Confidence (%) | Probability map |
|---|---|---|---|
Guaifenesin | Non-cardiotoxic (−) | 60 |
|
Quercetin | Non-cardiotoxic (−) | 60 |
|
2-Methoxy-4-Vinylphenol | Non-cardiotoxic (−) | 60 |
|
3-p-Coumaroylquinic acid | Non-cardiotoxic (−) | 50 |
|
Chlorogenic acid | Non-cardiotoxic (−) | 50 |
|
Lupeol | Potential cardiotoxic (+) | 5 |
|
Rutin | Potential cardiotoxic (+) | 60 |
|
beta-Caryophyllene | Potential cardiotoxic (+) | 50 |
|
Procyanidin B1 | Potential cardiotoxic (+) | 50 |
|
Nummularine R | Potential cardiotoxic (+) | 60 |
|
2-Isobutyl-3-methoxypyrazine | Potential cardiotoxic (+) | 60 |
|
Nummularine A | Potential cardiotoxic (+) | 50 |
|
Luteolin-7-O-glucoside | Potential cardiotoxic (+) | 50 |
|
