Figure 10 | Scientific Reports

Figure 10

From: White and gray matter integrity evaluated by MRI-DTI can serve as noninvasive and reliable indicators of structural and functional alterations in chronic neurotrauma

Figure 10

TBI causes structural abnormalities at the nodes of Ranvier. Coclustering of ankyrin G (AnkG, nodal protein) and contactin-associated protein (Caspr, paranodal protein) at the nodes of Ranvier after TBI. (A) Representative images of sections from sham, TBI, and rmTBI groups. Colocalization puncta intensity of AnkG and Caspr signals in (B) CCs, (C) LD, (D) VPL and VPM, (E) ic, and (F) ab of ipsilateral brain regions. Data are represented as the means ± SD (n = 4–10). *P < 0.05, compared with the sham group. +P < 0.05, compared with the TBI group.

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