Figure 1

Effects of taurine treatment on taurine-positive area and TAUT in brain tissue. Representative immunohistochemical staining images of taurine and quantitative analyses of taurine-positive area in the hippocampus (A, top row, bar = 200 µm; bottom row, bar = 50 µm, enlarged from the dashed line box) and cortex (B, top row, bar = 100 µm; bottom row, bar = 50 µm, enlarged from the dashed line box). Taurine-positive areas are visualized in brown. Data are expressed as the means ± SD of 5 hippocampal fields from five SAMP8 mice and 4 specific cortex areas from four SAMP8 mice of each group. Western blots of TAUT expression in the hippocampus (C) and cortex (D). Data are expressed as the means ± SD of quadruplicate samples of each group. *p < 0.05, Student’s t-test.