Figure 4

Clinical characteristics and biomarkers of PN patients with and without improvement on dupilumab therapy. (a) Representative clinical photos of PN patients who achieved clinically significant improvement in itch (responders) and those who did not (non-responders) after at least 6 months of dupilumab therapy. (b) AEC of dupilumab responders (R) versus non-responders (NR). (c) Percentage of patients with AEC > 0.3 K cells/μL in dupilumab R versus NR. (d) Percentage of patients with a history of atopy in dupilumab R versus NR. (e) Percentage of patients in each racial category that were dupilumab responders. AA African American, As Asian, CA Caucasian.