Figure 2 | Scientific Reports

Figure 2

From: Early screening of colorectal cancer using feature engineering with artificial intelligence-enhanced analysis of nanoscale chromatin modifications

Figure 2

Packing scaling D is sensitive to field carcinogenesis. (a) Chromatin packing scaling D in cells brushed from tumor site, healthy-appearing tissue located 4 cm away from tumor and from rectum (n = 10) showed significantly increase (p = 1.5 × 10–6,6.9 × 10–5, 3.6 × 10–7 respectively) compared to control patients (n = 20) but no significant difference among the three locations. (b) Rectal D is increased in patients with dysplasia regardless of anatomic location, right-sided (p = 0.017) and left-sided adenoma (p = 0.002) compared to control.

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