Figure 9
From: UTRN as a potential biomarker in breast cancer: a comprehensive bioinformatics and in vitro study
UTRN-related miRNAs in BRCA. (A, B) hsa-miR-7-5p and hsa-miR-877-5p, possible target miRNAs for UTRN through the prediction of ENCORI database, is down-expressed in BRCA from TCGA cohort. Hsa-miR-7-5p and hsa-miR-877-5p expression was negatively correlated with UTRN expression. Correlation test is conducted by the Pearson coefficient. p-value < 0.01 is the significance threshold. (C, D) The expression of hsa-miR-7-5p and hsa-miR-877-5p in human normal compared with that in breast cancer patients from TCGA-BRCA database (Wilcoxon-Mann–Whitney test). (E, F) Patients with low hsa-miR-7-5p and hsa-miR-877-5p expression were closely correlated with better overall survival (two-side log-rank test). (G) Forest map of possible miRNAs of UTRN.
