Figure 1 | Scientific Reports

Figure 1

From: Mendelian randomization analysis reveals causal associations of serum metabolites with sepsis and 28-day mortality

Figure 1

Overview of this Mendelian randomization (MR) analysis. Assumption 1: The genetic instruments are directly associated with the exposure. Assumption 2: Genetic instruments have no impact on the outcome and are independent of known and unknown confounders. Assumption 3: Genetic instruments are unrelated to the outcome and affect the outcome entirely through exposure.

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