Figure 7
Knockout of MKP5 attenuated the hepatoprotective effect of 6-Gingerol. (A, B) Serum ALT and AST level, (C) H&E staining and (D) necrotic area statistics, (E–H) Il-1β, Il-6, Tnf-α and Mcp1 mRNA expression, (I) TUNEL staining (red fluorescence indicates TUNEL positives cells) and (J) statistical analysis, (K–N) MKP5 protein and P38/JNK pathway protein detection. **P < 0.01 versus sham group; ##P < 0.01 versus I/R group; $$P < 0.01 versus I/R group; ##P < 0.01 versus I/R +100 mg/kg group.
