Figure 4
From: Phylogeny and structural modeling of the transcription factor CsqR (YihW) from Escherichia coli
Schematic representation of the workflow used for structural modeling of CsqR. NTD—N-terminal domain, CTD—C-terminal domain. First, AlphaFold models were obtained for CsqR-s and CsqR-l (CsqR-s-AF and CsqR-l-AF models, respectively). The interdomain linker of CsqR-s-AF was predicted with a low confidence suggesting a loop region. To predict an alternative structure of CsqR-s with the more prominent structural arrangement of the interdomain linker, we obtained the I-TASSER model of CsqR-s using the CsqR-l-AF model as a template. The goal was to check if both types of CsqR-s models would fold to the similar structure of the linker after MDS.
