Figure 5 | Scientific Reports

Figure 5

From: Dihydrotanshinone I exhibits antitumor effects via β-catenin downregulation in papillary thyroid cancer cell lines

Figure 5

Effects of DHT on gene expression. (A) Venn diagrams represented the comparison of downregulated (in red) and upregulated (in green) genes between K1 and BCPAP lines treated with 2.5 μM DHT, after RNA-seq data analysis. Within the intersection of the circles are indicated the alterated genes which are shared between the two cell lines. (B) Heat maps obtained after gene expression analysis following treatment with DHT (K1 DHT and BCPAP DHT) or with the vehicle (K1 DMSO and BCPAP DMSO). (C) Top5 down-regulated pathways in the two cell lines after DHT treatment, examined independently.

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