Figure 7

Disruption of the BMAL1/REV-ERBα circadian rhythmic loop resulted in elevated factors contributing to fat depletion, including NT-proBNP, IL-6 and NE. (A) Plasma levels of NT-proBNP. (B) IL-6 content in WAT. (C) IL-6 content in BAT. (D) NE content in WAT. (E) NE content in BAT. Data are mean ± SD, n = 6. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.