Table 5 Group differentiated analysis of BCA parameters stratified by MCID for FEV1.

From: Body composition impacts outcome of bronchoscopic lung volume reduction in patients with severe emphysema: a fully automated CT-based analysis

Parameter

Pre-implant (baseline)

Follow-Up (6-month)

p-value

ΔFEV1, mL

 

 ≤ 100

 > 100

  

n = 114

n = 86

Muscle, BAR

1.63 (0.9–3.2)

1.53 (0.8–3.2)

1.72 (1.0–2.6)

 < 0.01

ΔMuscle, BAR

-

–0.07

0.068

 < 0.01

ΔMuscle, BAR%

-

–5

3.4

 < 0.01

TAT, BAR

2.86 (0.25–10.3)

3.16 (0.3–10.3)

3.6 (1.0–2.6)

n.s

ΔTAT, BAR

-

0.12

0.13

n.s

ΔTAT, BAR%

-

4

3.7

n.s

SAT, BAR

1.94 (0.8–7.9)

1.8 (0.09–6.4)

2.2 (0.13–7.9)

n.s

ΔSAT, BAR

-

0.065

0.063

n.s

ΔSAT, BAR%

-

3.08

3.12

n.s

PAT, BAR

0.16 (0.03–0.54)

0.16 (0.04–0.54)

0.18 (0.06–0.5)

n.s

ΔPAT, BAR

-

0.0039

0.0044

n.s

ΔPAT, BAR%

-

2.97

2.50

n.s

IMAT, BAR

0.54 (0.1–1.7)

0.49 (0.13–1.4)

0.57 (0.16–1.7)

< 0.05

ΔIMAT, BAR

-

–0.003

0.0045

< 0.05

ΔIMAT, BAR%

-

–0.62

0.60

< 0.05

EAT, BAR

0.08 (0.01–0.28)

0.08 (0.02–0.20)

0.08 (0.03–0.28)

n.s

ΔEAT, BAR

-

0.001

0.0043

n.s

ΔEAT, BAR%

-

1.2

4.38

n.s

  1. FEV1 forced expiratory volume in 1 s, MCID minimally clinical important difference, BAR bone adjusted ratio, IMAT intra- and intermuscular adipose tissue, EAT epicardial adipose tissue, PAT paracardial adipose tissue, SAT subcutaneous adipose tissue, TAT total adipose tissue. n.s. non-significant. Statistically significant differences between groups tested with Mann–Whitney-test.
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