Figure 3
From: Translational research of boron neutron capture therapy for spinal cord gliomas using rat model
Kaplan–Meier curves, the BBB scale and the in vivo biodistribution of boron of F98 and 9L SCG models. (a,b) These Kaplan–Meier curves show the survival time of F98 or 9L rat SCG models after implantation of each cell line (a; 104 cells, b; 105 cells). Survival times (days) are plotted. Four groups were prepared; F98 104 cells (n = 8), F98 105 cells (n = 13), 9L 104 cells (n = 7), and 9L 105 cells (n = 13). Statistical analysis was performed using the log rank test. (c,d) These figures show the BBB scale in the case of implantation of F98 or 9L and 104 cells or 105 cells. The error bar indicates the standard deviation (SD). Statistical analysis was performed using the multivariate analysis of variance (MANOVA). e–f, These figures show the time course of boron concentration in each organ after intravenous administration of BPA (250 mg /kg b.w.) to the F98 or 9L rat SCG models (e; F98, f; 9L). All the bars indicate standard deviation (SD; F98 2.5 h: n = 8, 6 h: n = 4, 24 h: n = 4, 9L 2.5 h: n = 6, 6 h: n = 4, 24 h: n = 4).
