Table 2 The summary of the boron concentrations in each tissue of the F98 and 9L rat SCG models.
From: Translational research of boron neutron capture therapy for spinal cord gliomas using rat model
Cell line | Boron compound (dose) | Timea (h) | nb | Boron concentrations ± SD (μg B/g) | Ratios | |||||
|---|---|---|---|---|---|---|---|---|---|---|
Tumor | Spinal cord | Brain | Blood | T/SCc | T/Bld | Bl/SCe | ||||
F98 rat glioma | BPA (250 mg/kg) | 2.5 | 8 | 26.6 ± 5.8 | 5.3 ± 1.3 | 5.5 ± 0.5 | 6.7 ± 0.7 | 5.0 | 4.0 | 1.3 |
6 | 4 | 16.3 ± 3.6 | 4.0 ± 1.1 | 4.2 ± 0.6 | 4.7 ± 0.6 | 4.1 | 3.5 | 1.2 | ||
24 | 4 | 3.0 ± 0.4 | 0.8 ± 0.2 | 1.1 ± 0.5 | 1.1 ± 0.2 | 3.6 | 2.8 | 1.3 | ||
9L rat gliosarcoma | 2.5 | 6 | 15.3 ± 4.5 | 4.2 ± 0.6 | 5.0 ± 0.7 | 5.9 ± 0.5 | 3.7 | 2.6 | 1.4 | |
6 | 5 | 12.6 ± 2.3 | 3.3 ± 0.7 | 4.7 ± 1.0 | 5.0 ± 0.9 | 3.8 | 2.5 | 1.5 | ||
24 | 4 | 6.0 ± 0.8 | 2.0 ± 0.7 | 1.8 ± 0.6 | 1.9 ± 0.5 | 3.0 | 3.2 | 1.0 | ||