Table 2 The summary of the boron concentrations in each tissue of the F98 and 9L rat SCG models.

From: Translational research of boron neutron capture therapy for spinal cord gliomas using rat model

Cell line

Boron compound (dose)

Timea (h)

nb

Boron concentrations ± SD (μg B/g)

Ratios

Tumor

Spinal cord

Brain

Blood

T/SCc

T/Bld

Bl/SCe

F98 rat glioma

BPA (250 mg/kg)

2.5

8

26.6 ± 5.8

5.3 ± 1.3

5.5 ± 0.5

6.7 ± 0.7

5.0

4.0

1.3

6

4

16.3 ± 3.6

4.0 ± 1.1

4.2 ± 0.6

4.7 ± 0.6

4.1

3.5

1.2

24

4

3.0 ± 0.4

0.8 ± 0.2

1.1 ± 0.5

1.1 ± 0.2

3.6

2.8

1.3

9L rat gliosarcoma

2.5

6

15.3 ± 4.5

4.2 ± 0.6

5.0 ± 0.7

5.9 ± 0.5

3.7

2.6

1.4

6

5

12.6 ± 2.3

3.3 ± 0.7

4.7 ± 1.0

5.0 ± 0.9

3.8

2.5

1.5

24

4

6.0 ± 0.8

2.0 ± 0.7

1.8 ± 0.6

1.9 ± 0.5

3.0

3.2

1.0

  1. aTime indicates the time after the termination intravenous administration.
  2. bn indicates the number of the Fischer rats.
  3. cT/SC: Tumor to Spinal cord (SC) ratio.
  4. dT/Bl: Tumor to Blood ratio.
  5. eBl/SC: Blood to Spinal Cord (SC) ratio.