Table 1 The synthesis of (9R)-HHC and (9S)-HHC at different scales.
Entry | Synthesis scale (∆8-THC mass), g | Mass of 5% Pd/C per 1 g of ∆8-THC, mg | ∆8-THC concentration, g/L | Duration of the reduction, days | 9R:9S molar ratio |
|---|---|---|---|---|---|
1 | 10 | 50 | 200 | 2 | 3:1 |
2 | 10 | 20 | 50 | 2 | 3:2 |
3 | 250 | 50 | 200 | 5 | 3:1 |
4 | 1000 | 50 | 250 | 14 | 3:1 |