Figure 2

(A) Effects of the studied compounds on the production of nitric oxide (NO) in LPS-stimulated RAW264.7 macrophages. Cells were treated with the studied compounds at concentration 100 µg/mL plus LPS (1 μg/mL) or LPS alone for 24 h. Sulindac (NSAID) was used as a positive control. (B) Cytotoxic effect of the studied compounds and Sulindac on Raw-264.7 macrophages at concentrations (100 μg/mL). Values are expressed as the means ± SD (n = 3) p < 0.0001 (versus LPS alone, 2A).