Figure 5 | Scientific Reports

Figure 5

From: Apigetrin ameliorates doxorubicin prompted testicular damage: biochemical, spermatological and histological based study

Figure 5

Micro-images of the adult albino rat testicles (H&E, 400X): (A) Control group presenting impenetrable germinal epithelium exhibiting germ cells & tapered luminal area with sperms; (B) APG treated group showing compacted seminiferous tubules with less IS and luminal part filled with germ cells; (C) DOX exposed group showing sloughing of the epithelial layer, vacant lumen & degenerated area of IS; (D) DOX + APG co-administered group demonstrating renovation in epithelial part as well as TL filled with ST and recovered deteriorated IS. DOX: Doxorubicin; APG: Apigetrin TL: Tubular lumen; EH: Seminiferous epithelial height; IS: Interstitial spaces; SG: Spermatogonia; PS: Primary spermatocytes; SS: Secondary Spermatocytes; ST: Spermatids.

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